Robert W Robey Selected Research

ATP-Binding Cassette Transporters (ABC Transporters)

1/2021	Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance.
10/2019	Porphyrin-lipid assemblies and nanovesicles overcome ABC transporter-mediated photodynamic therapy resistance in cancer cells.
1/2018	Revisiting the role of ABC transporters in multidrug-resistant cancer.
10/2013	Overlapping substrate and inhibitor specificity of human and murine ABCG2.
1/2012	A pharmacodynamic study of the P-glycoprotein antagonist CBT-1® in combination with paclitaxel in solid tumors.
9/2011	The controversial role of ABC transporters in clinical oncology.
5/2011	Rapid detection of ABC transporter interaction: potential utility in pharmacology.
10/2010	ABC transporters: unvalidated therapeutic targets in cancer and the CNS.
8/2010	Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib.
8/2009	Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.

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Robert W Robey Research Topics

Disease

45	Neoplasms (Cancer) 05/2022 - 03/2002
14	Breast Neoplasms (Breast Cancer) 01/2022 - 06/2002
6	T-Cell Lymphoma (Lymphoma, T Cell) 10/2016 - 06/2004
3	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 05/2013 - 07/2010
2	Neuroblastoma 01/2021 - 04/2008
2	Infections 01/2020 - 07/2010
2	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 01/2018
2	Kidney Neoplasms (Kidney Cancer) 02/2013 - 03/2006
2	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 12/2011 - 01/2010
2	Carcinoma (Carcinomatosis) 08/2009 - 02/2005
2	Renal Cell Carcinoma (Grawitz Tumor) 02/2009 - 07/2004
2	Glioblastoma (Glioblastoma Multiforme) 02/2008 - 07/2005
1	Ovarian Epithelial Carcinoma 01/2021
1	Uveal melanoma 01/2021
1	Rhabdomyosarcoma 01/2021
1	Carcinogenesis 05/2020
1	Mycoplasma Infections 01/2020
1	Hypoxia (Hypoxemia) 11/2019
1	Adenocarcinoma 11/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2014
1	Burkitt Lymphoma (Burkitt's Lymphoma) 09/2013
1	Glioma (Gliomas) 02/2013
1	Neutropenia 01/2012
1	Hematologic Neoplasms (Hematological Malignancy) 12/2011

Drug/Important Bio-Agent (IBA)

18	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021 - 03/2006
18	Pharmaceutical PreparationsIBA 01/2021 - 06/2002
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
13	Adenosine Triphosphate (ATP)IBA 01/2021 - 06/2002
12	Histone Deacetylase InhibitorsIBA 01/2021 - 03/2002
12	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2019 - 07/2004
11	romidepsin (FK228)FDA Link 01/2021 - 03/2002
5	Mitoxantrone (Novantrone)FDA LinkGeneric 08/2009 - 07/2005
4	multidrug resistance-associated protein 1IBA 10/2019 - 03/2008
4	DepsipeptidesIBA 05/2015 - 03/2002
4	Tyrosine Kinase InhibitorsIBA 08/2010 - 03/2007
3	Photosensitizing Agents (Photosensitizers)IBA 10/2019 - 02/2005
3	TubulinIBA 01/2018 - 12/2007
3	Vorinostat FDA Link 12/2014 - 12/2011
3	Biomarkers (Surrogate Marker)IBA 06/2014 - 07/2010
3	Gefitinib (Iressa)FDA Link 02/2009 - 03/2007
3	ErbB Receptors (EGF Receptor)IBA 02/2009 - 03/2007
2	PorphyrinsIBA 01/2022 - 10/2019
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 05/2015
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2021 - 10/2016
2	Messenger RNA (mRNA)IBA 05/2020 - 02/2013
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 10/2019 - 02/2005
2	Topotecan (Hycamtin)FDA LinkGeneric 06/2014 - 08/2009
2	tariquidar (XR9576)IBA 01/2012 - 02/2011
2	Irinotecan (Camptosar)FDA LinkGeneric 08/2009 - 01/2008
2	Amino Acids FDA Link 02/2009 - 11/2002
2	alvocidib (flavopiridol)IBA 02/2009 - 01/2008
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2009 - 11/2007
2	Methotrexate (Mexate)FDA LinkGeneric 01/2008 - 09/2002
2	Antineoplastic Agents (Antineoplastics)IBA 09/2006 - 06/2004
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 05/2022
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021
1	trametinibIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	lens intrinsic protein MP 38 (MP38)IBA 01/2021
1	2- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA 01/2021
1	taxaneIBA 01/2021
1	Vinca AlkaloidsIBA 01/2021
1	ON 01910IBA 01/2021
1	PlatinumIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	ulixertinibIBA 01/2021
1	LeptinIBA 05/2020
1	Estrogen ReceptorsIBA 05/2020
1	Leptin ReceptorsIBA 05/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020
1	LigandsIBA 01/2020
1	CeramidesIBA 01/2020
1	Tiopronin (Thiola)FDA Link 01/2020
1	matrigelIBA 11/2019
1	Colchicine FDA LinkGeneric 11/2019
1	Oxygen (Dioxygen)IBA 11/2019
1	LipidsIBA 10/2019
1	bifonazoleIBA 01/2019
1	Clotrimazole (Lotrimin)FDA LinkGeneric 01/2019
1	Silybin (Lagosa)IBA 01/2018
1	Mitogen-Activated Protein KinasesIBA 10/2016
1	AnnexinsIBA 12/2014
1	icotinibIBA 06/2014
1	XenobioticsIBA 10/2013
1	Subfamily B ATP Binding Cassette TransporterIBA 09/2013
1	apicidinIBA 02/2013
1	entinostat (MS 275)IBA 02/2013
1	olaparibIBA 01/2012
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2012
1	Sildenafil Citrate (Viagra)FDA Link 04/2011

Therapy/Procedure

12	Therapeutics 01/2021 - 06/2004
5	Drug Therapy (Chemotherapy) 01/2021 - 09/2006
3	Aftercare (After-Treatment) 02/2013 - 12/2007
2	Photochemotherapy (Photodynamic Therapy) 10/2019 - 02/2005
1	Treatment Delay 01/2021
1	Bioreactors (Bioreactor) 11/2019
1	Traction 12/2014
1	Duration of Therapy 12/2014